Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced Hamster Cheek Pouch Carcinogenesis by a 5-Lipoxygenase Inhibitor, Garcinol
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منابع مشابه
Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line.
In order to investigate the involvement of cyclooxygenase (COX)-2 in oral carcinogenesis and chemoprevention for it, we examined the COX-2 expression during dimethylbenzanthracene (DMBA)-induced hamster cheek pouch carcinogenesis and the inhibitory effect of sulindac, a non-steroidal anti-inflammatory drug (NSAID), on the carcinogenesis and its derived squamous carcinoma cell line HCPC-1. From ...
متن کاملCarcinogenesis in the Hamster Cheek Pouch
Pouches from three experimental and one control animal were excised for analysis at various times during the first week and thereafter each week of carcinogen application (9,10-dimethyl-l ,~-benzanthracene) until the 131h week, at which time large tumors were present in all remaining aninmls. IIistologic progression from normal through inflanmmtion, uniform hyperplasia, localized premalignant h...
متن کاملDiurnal variation of gamma-glutamyl transpeptidase activity during DMBA-induced hamster buccal pouch carcinogenesis.
OBJECTIVE The aim of the present study is to assess the diurnal variation of gamma-glutamyl transpeptidase (GGT) during 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch carcinogenesis. MATERIALS AND METHODS The right buccal pouches of 108 Syrian golden hamsters, divided into three experimental groups, were treated three times weekly with 0.5% DMBA in mineral oil over an 11-w...
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UNLABELLED Abnormalities in the p53 gene are regarded as the most consistent genetic abnormalities detected in head and neck squamous cell carcinogenesis. Two new members of the p53 gene family, p73 at the 1p36 region and p63 at the 3q27-29 region, have recently been identified. They share considerable sequence homology with p53 in the transactivation, DNA binding, and oligomerization domains, ...
متن کاملChemotherapeutic effect of Ellagic acid encapsulated chitosan nanoparticles on DMBA induced hamster buccal pouch carcinogenesis
April June 2017 963 JCPS Volume 10 Issue 2 Chemotherapeutic effect of Ellagic acid encapsulated chitosan nanoparticles on DMBA induced hamster buccal pouch carcinogenesis S. Mirunalini*, V. Arulmozhi and S. Isabella Department of Biochemistry and Biotechnology, Annamalai University, Annamalainagar – 608 002 *Corresponding author: E-Mail:[email protected], Tel: 91 4144 238343, Fax: 91 4144 ...
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ژورنال
عنوان ژورنال: Nutrition and Cancer
سال: 2012
ISSN: 0163-5581,1532-7914
DOI: 10.1080/01635581.2012.718032